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Bacteroides uniformis

Bacteroides uniformis plays a role in the degradation of a specific type of soybean isoflavone called genistein.

Taxonomic Level: Species 

Family: Bacteroidaceae  

Properties: Gram-negative, Anaerobic, Nonsporulating  

Additional Information: Bacteroides uniformis is a gut bacterium that likely contributes to the degradation of a specific type of soybean isoflavone called genistein (found abundantly in soy products) in individuals who degrade genistein rapidly. The chemical structure of B. uniformis resembles the naturally occurring hormone estrogen, which is why scientists believe it has so many health implications, including properties which may reduce the risk of some forms of cancer and atherosclerosis. This microbe also plays a unique role in butanoate metabolism, enhancing the process through the use of pectin (a polysaccharide commonly present in ripe fruits). This enhancement increases the production of butyrate and the inhibitory neurotransmitter GABA, contributing to the strength of the gut barrier and even mental health (please see the functional analysis section of your report to learn more about butyrate and GABA).

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